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Image Search Results
Journal: Particle and Fibre Toxicology
Article Title: Aluminium oxide nanoparticles compromise spatial memory performance and proBDNF-mediated neuronal function in the hippocampus of rats
doi: 10.1186/s12989-022-00477-8
Figure Lengend Snippet: Effects of aluminaNPs on mBDNF-CREB and proBDNF-RhoA signaling pathway. The levels of A mBDNF, B CREB, C proBDNF and D RhoA in the hippocampus. *, P < 0.05, versus control group. E Blocking proBDNF receptor p75 NTR activation can mitigate memory deficits. Data are presented as mean ± SEM. *, P < 0.05, versus other groups. The number of rats in each group was indicated in each legend
Article Snippet: The membranes were blocked with 5% non-fat skimmed milk for one hour and incubated with the primary mouse anti-proBDNF (1:500; Cat#sc-65,514, Santa Cruz Biotechnology),
Techniques: Control, Blocking Assay, Activation Assay